Yan Zhou;Huajun Zheng;Yangyi Chen;Lei Zhang;Kai Wang;Jing Guo;Zhen Huang;Bo Zhang;Wei Huang;Ke Jin;Tonghai Dou;Masami Hasegawa;Li Wang;Yuan Zhang;Jie Zhou;Lin Tao;志伟 曹;Yixue Li;Tomas Vinar;Brona Brejova;Dan Brown;Ming Li;David J. Miller;David Blair;Yang Zhong;竺 陈;Feng Liu;Wei Hu;Zhi Qin Wang;Qin Hua Zhang;怀东 宋;赛娟 陈;Xuenian Xu;Bin Xu;Chuan Ju;Yucheng Huang;Paul J. Brindley;Donald P. McManus;Zheng Feng;Ze Guang Han;Gang Lu;Shuangxi Ren;Yuezhu Wang;Wenyi Gu;Hui Kang;Jie Chen;Xiaoyun Chen;Shuting Chen;Lijun Wang;Jie Yan;Biyun Wang;Xinyan Lv;Lei Jin;Bofei Wang;Shiyin Pu;Xianglin Zhang;Wei Zhang;Qiuping Hu;Genfeng Zhu;军 王;俊 余;Jian Wang;焕明 杨;Zemin Ning;Matthew Beriman;Chia Lin Wei;Yijun Ruan;国屏 赵;Shengyue Wang
Chinese National Human Genome Center;Fudan University;Shanghai Center for Bioinformation Technology;University of Waterloo;James Cook University Queensland;Shanghai Jiao Tong University;Chinese Center for Disease Control and Prevention;National Engineering Center for Biochip at Shanghai;George Washington University;Queensland Institute of Medical Research;Chinese Academy of Sciences;Wellcome Sanger Institute;Agency for Science; Technology and Research;CAS - Shanghai Institute for Biological Sciences
发表时间：2009-7-16
期 刊：Nature
语 言：English
U R L： http://www.scopus.com/inward/record.url?scp=67650786530&partnerID=8YFLogxK
Schistosoma japonicum is a parasitic flatworm that causes human schistosomiasis, which is a significant cause of morbidity in China and the Philippines. Here we present a draft genomic sequence for the worm. The genome provides a global insight into the molecular architecture and host interaction of this complex metazoan pathogen, revealing that it can exploit host nutrients, neuroendocrine hormones and signalling pathways for growth, development and maturation. Having a complex nervous system and a well-developed sensory system, S. japonicum can accept stimulation of the corresponding ligands as a physiological response to different environments, such as fresh water or the tissues of its intermediate and mammalian hosts. Numerous proteases, including cercarial elastase, are implicated in mammalian skin penetration and haemoglobin degradation. The genomic information will serve as a valuable platform to facilitate development of new interventions for schistosomiasis control.
Scopus度量
| 年份 | CiteScore | SJR | SNIP |
|---|---|---|---|
| 1996 | |||
| 1997 | |||
| 1998 | |||
| 1999 | 15.599 | 7.183 | |
| 2000 | 11.917 | 6.845 | |
| 2001 | 9.874 | 6.735 | |
| 2002 | 10.114 | 7.208 | |
| 2003 | 11.384 | 7.504 | |
| 2004 | 11.222 | 7.523 | |
| 2005 | 10.333 | 7.199 | |
| 2006 | 9.702 | 7.156 | |
| 2007 | 10.344 | 7.097 | |
| 2008 | 13.17 | 7.321 | |
| 2009 | 15.185 | 8.2 | |
| 2010 | 16.465 | 8.23 | |
| 2011 | 53.1 | 17.598 | 8.652 |
| 2012 | 51 | 17.546 | 8.409 |
| 2013 | 50.9 | 19.69 | 8.482 |
| 2014 | 49.9 | 18.78 | 7.946 |
| 2015 | 51.6 | 19.669 | 8.052 |
| 2016 | 49.2 | 18.389 | 7.901 |
| 2017 | 53.7 | 17.875 | 8.647 |
| 2018 | 55.7 | 16.345 | 9.448 |
| 2019 | 51 | 14.047 | 8.82 |
| 2020 | 54.6 |
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