Ruiqiang Li;Hongmei Zhu;Jue Ruan;Wubin Qian;Xiaodong Fang;Zhongbin Shi;Yingrui Li;Shengting Li;Gao Shan;Karsten Kristiansen;Songgang Li;焕明 杨;Jian Wang;军 王
CAS - Beijing Institute of Genomics;University of Copenhagen
发表时间:2010-2
期 刊:Genome Research
语 言:English
U R L: http://www.scopus.com/inward/record.url?scp=75649124547&partnerID=8YFLogxK
Next-generation massively parallel DNA sequencing technologies provide ultrahigh throughput at a substantially lower unit data cost; however, the data are very short read length sequences, making de novo assembly extremely challenging. Here, we describe a novel method for de novo assembly of large genomes from short read sequences. We successfully assembled both the Asian and African human genome sequences, achieving an N50 contig size of 7.4 and 5.9 kilobases (kb) and scaffold of 446.3 and 61.9 kb, respectively. The development of this de novo short read assembly method creates new opportunities for building reference sequences and carrying out accurate analyses of unexplored genomes in a cost-effective way.
医学与生命科学
Scopus度量
年份 | CiteScore | SJR | SNIP |
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1996 | |||
1997 | |||
1998 | |||
1999 | 5.892 | 2.261 | |
2000 | 5.531 | 2.121 | |
2001 | 6.272 | 2.112 | |
2002 | 6.339 | 2.041 | |
2003 | 6.795 | 2.277 | |
2004 | 7.78 | 2.29 | |
2005 | 7.935 | 2.377 | |
2006 | 6.922 | 2.229 | |
2007 | 9.062 | 2.443 | |
2008 | 8.588 | 2.075 | |
2009 | 10.404 | 2.56 | |
2010 | 12.476 | 2.551 | |
2011 | 24.6 | 14.017 | 2.966 |
2012 | 25.4 | 14.306 | 3.06 |
2013 | 25.8 | 15.228 | 2.865 |
2014 | 26.3 | 14.817 | 2.917 |
2015 | 28.2 | 14.278 | 2.914 |
2016 | 22.6 | 12.594 | 2.395 |
2017 | 22 | 12.367 | 2.408 |
2018 | 18 | 10.205 | 2.499 |
2019 | 16.8 | 9.245 | 2.534 |
2020 | 19.3 | ||
2021 |
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