一公 施
Princeton University
发表时间:2004-6-25
期 刊:Cell
语 言:English
U R L: http://www.scopus.com/inward/record.url?scp=2942746419&partnerID=8YFLogxK
Caspases execute cell death. The mechanism of effector caspase activation primarily involves reorganization of active site loops following the activation cleavage. The Induced Proximity hypothesis, originally proposed to explain the activation of initiator caspases, has recently been reinterpreted to be proximity-driven dimerization of initiator caspases, and consequently their activation. The evidence supporting these models is critically evaluated and other possible mechanisms for initiator caspase activation are discussed.
医学与生命科学
化合物
Scopus度量
年份 | CiteScore | SJR | SNIP |
---|---|---|---|
1996 | |||
1997 | |||
1998 | |||
1999 | 43.449 | 6.332 | |
2000 | 36.711 | 5.999 | |
2001 | 29.247 | 5.155 | |
2002 | 28.027 | 4.956 | |
2003 | 28.284 | 4.99 | |
2004 | 25.704 | 5.002 | |
2005 | 25.262 | 4.648 | |
2006 | 23.831 | 4.889 | |
2007 | 25.228 | 5.206 | |
2008 | 25.274 | 5.631 | |
2009 | 26.21 | 6.527 | |
2010 | 25.629 | 6.426 | |
2011 | 56.8 | 25.74 | 6.681 |
2012 | 55.5 | 25.117 | 6.9 |
2013 | 52.4 | 28.254 | 6.842 |
2014 | 53.9 | 28.505 | 6.776 |
2015 | 54.6 | 27.712 | 6.29 |
2016 | 53.5 | 27.691 | 6.043 |
2017 | 54.9 | 25.137 | 5.947 |
2018 | 56.2 | 25.976 | 6.769 |
2019 | 58.7 | 24.698 | 7.114 |
2020 | 62 | ||
2021 |
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